An Association between l-Arginine/Asymmetric Dimethyl Arginine Balance, Obesity, and the Age of Asthma Onset Phenotype

Rationale: Increasing body mass index (BMI) has been associated with less fractional exhaled nitric oxide (Fe(NO)). This may be explained by an increase in the concentration of asymmetric dimethyl arginine (ADMA) relative to l-arginine, which can lead to greater nitric oxide synthase uncoupling. Obj...

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Main Authors: Holguin, Fernando, Comhair, Suzy A. A., Hazen, Stanley L., Powers, Robert W., Khatri, Sumita S., Bleecker, Eugene R., Busse, William W., Calhoun, William J., Castro, Mario, Fitzpatrick, Anne M., Gaston, Benjamin, Israel, Elliot, Jarjour, Nizar N., Moore, Wendy C., Peters, Stephen P., Teague, W. Gerald, Chung, Kian Fan, Erzurum, Serpil C., Wenzel, Sally E.
Format: Artigo
Language:Inglês
Published: American Thoracic Society 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570651/
https://ncbi.nlm.nih.gov/pubmed/23204252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201207-1270OC
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