Oxygen-Independent Stabilization of Hypoxia Inducible Factor (HIF)-1 during RSV Infection

BACKGROUND: Hypoxia-inducible factor 1 (HIF)-1α is a transcription factor that functions as master regulator of mammalian oxygen homeostasis. In addition, recent studies identified a role for HIF-1α as transcriptional regulator during inflammation or infection. Based on studies showing that respirat...

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Main Authors: Haeberle, Helene A., Dürrstein, Carin, Rosenberger, Peter, Hosakote, Yashoda M., Kuhlicke, Johannes, Kempf, Volkhard A. J., Garofalo, Roberto P., Eltzschig, Holger K.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2008
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556398/
https://ncbi.nlm.nih.gov/pubmed/18839041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003352
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