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Spectroscopic and Kinetic Studies of Perturbed Trinuclear Copper Clusters: The Role of Protons in Reductive Cleavage of the O-O Bond in the Multicopper Oxidase Fet3p

The multicopper oxidase Fet3p couples four 1e(−) oxidations of substrate to the 4e(−)reduction of O(2) to H(2)O. Fet3p uses four Cu atoms to accomplish this reaction: the type 1, type 2, and coupled binuclear type 3 sites. The type 2 and type 3 sites together form a trinuclear Cu cluster (TNC) which...

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Bibliografiske detaljer
Main Authors: Augustine, Anthony J., Quintanar, Liliana, Stoj, Christopher S., Kosman, Daniel J., Solomon, Edward I.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556285/
https://ncbi.nlm.nih.gov/pubmed/17918838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja073905m
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