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MEDME: An experimental and analytical methodology for the estimation of DNA methylation levels based on microarray derived MeDIP-enrichment

DNA methylation is an important component of epigenetic modifications that influences the transcriptional machinery and is aberrant in many human diseases. Several methods have been developed to map DNA methylation for either limited regions or genome-wide. In particular, antibodies specific for met...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pelizzola, Mattia, Koga, Yasuo, Urban, Alexander Eckehart, Krauthammer, Michael, Weissman, Sherman, Halaban, Ruth, Molinaro, Annette M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556264/
https://ncbi.nlm.nih.gov/pubmed/18765822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.080721.108
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