Deletion of both ICAM-1 and C3 Enhances Severity of Experimental Autoimmune Encephalomyelitis Compared to C3-Deficient Mice

Multiple sclerosis (MS) is an autoimmune disease characterized by central nervous system (CNS) inflammation and leukocyte infiltration, demyelination of neurons, and blood-brain barrier breakdown. The development of experimental autoimmune encephalomyelitis (EAE), the animal model for MS is dependen...

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Главные авторы: Smith, Sherry S., Ludwig, Michael, Wohler, Jillian E., Bullard, Daniel C., Szalai, Alex J., Barnum, Scott R.
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556246/
https://ncbi.nlm.nih.gov/pubmed/18634851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2008.07.005
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