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Complement in Experimental Autoimmune Encephalomyelitis Revisited: C3 is Required for Development of Maximal Disease

Complement per se has been shown to play an important role in demyelinating disease but controversy remains regarding the role of C3 in the development and progression of experimental autoimmune encephalomyelitis (EAE), the animal model for multiple sclerosis. In this study we used C3(-/-) mice to c...

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Detalhes bibliográficos
Main Authors: Szalai, Alexander J., Hu, Xianzhen, Adams, Jillian E., Barnum, Scott R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1986644/
https://ncbi.nlm.nih.gov/pubmed/17353050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2007.02.002
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