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αE-catenin controls cerebral cortical size by regulating hedgehog signalling pathway

During development cells monitor and adjust their rates of accumulation to produce predetermined-size organs; however, responsible for this mechanisms remain unknown. We show here that central nervous system-specific deletion of the essential adherens junction gene, αE-catenin, causes abnormal activ...

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Autori principali: Lien, Wen-Hui, Klezovitch, Olga, Fernandez, Tania E., Delrow, Jeff, Vasioukhin, Valeri
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556178/
https://ncbi.nlm.nih.gov/pubmed/16543460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1121449
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