IKKα, a critical regulator of epidermal differentiation and a suppressor of skin cancer

IκB kinase α (IKKα), one of the two catalytic subunits of the IKK complex involved in nuclear factor κB (NF-κB) activation, also functions as a molecular switch that controls epidermal differentiation. This unexpected function requires IKKα nuclear translocation but does not depend on its kinase act...

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Main Authors: Descargues, Pascal, Sil, Alok K, Karin, Michael
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2008
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New EMBO Member's Review
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556095/
https://ncbi.nlm.nih.gov/pubmed/18818691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.196
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