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High-Resolution Mapping of Expression-QTLs Yields Insight into Human Gene Regulation

Recent studies of the HapMap lymphoblastoid cell lines have identified large numbers of quantitative trait loci for gene expression (eQTLs). Reanalyzing these data using a novel Bayesian hierarchical model, we were able to create a surprisingly high-resolution map of the typical locations of sites t...

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Detalhes bibliográficos
Main Authors: Veyrieras, Jean-Baptiste, Kudaravalli, Sridhar, Kim, Su Yeon, Dermitzakis, Emmanouil T., Gilad, Yoav, Stephens, Matthew, Pritchard, Jonathan K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556086/
https://ncbi.nlm.nih.gov/pubmed/18846210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000214
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