Altered Specificity of Hint-W123Q Supports a Role for Hint Inhibition by Asw in Avian Sex Determination

Hint is a universally conserved, dimeric AMP-lysine hydrolase encoded on the avian Z chromosome. Tandemly repeated on the female-specific W chromosome, Asw is a potentially sex-determining, dominant negative Hint dimerization partner whose substrate-interacting residues were specifically altered in...

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Autores principales: Parks, Kristen P., Seidle, Heather, Wright, Nathan, Sperry, Jeffrey B., Bieganowski, Pawel, Howitz, Konrad, Wright, Dennis L., Brenner, Charles
Formato: Artigo
Lenguaje:Inglês
Publicado: 2004
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556054/
https://ncbi.nlm.nih.gov/pubmed/15507519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00204.2004
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