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Altered Specificity of Hint-W123Q Supports a Role for Hint Inhibition by Asw in Avian Sex Determination
Hint is a universally conserved, dimeric AMP-lysine hydrolase encoded on the avian Z chromosome. Tandemly repeated on the female-specific W chromosome, Asw is a potentially sex-determining, dominant negative Hint dimerization partner whose substrate-interacting residues were specifically altered in...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2556054/ https://ncbi.nlm.nih.gov/pubmed/15507519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00204.2004 |
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