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Fhit-nucleotide specificity probed with novel fluorescent and fluorogenic substrates
Fhit, a member of the Histidine Triad superfamily of nucleotide-binding proteins, binds and cleaves diadenosine polyphosphates and functions as a tumor suppressor in human epithelial cancers. Function of Fhit in tumor suppression does not require diadenosine polyphosphate cleavage but correlates wit...
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Hlavní autoři: | , , , |
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Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
2000
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Témata: | |
On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2556043/ https://ncbi.nlm.nih.gov/pubmed/10671479 |
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