Suppression of Lipopolysaccharide-stimulated Tumor Necrosis Factor-α Production by Adiponectin Is Mediated by Transcriptional and Post-transcriptional Mechanisms

Adiponectin is an adipokine with potent anti-inflammatory properties. Treatment of macrophages with adiponectin results in a suppression of lipopolysaccharide (LPS)-stimulated cytokine production. Here we investigated the transcriptional and post-transcriptional mechanisms by which adiponectin suppr...

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Detalhes bibliográficos
Main Authors: Park, Pil-Hoon, Huang, Honglian, McMullen, Megan R., Mandal, Palash, Sun, Lei, Nagy, Laura E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556004/
https://ncbi.nlm.nih.gov/pubmed/18678874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802787200
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