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Activation of the DNA Damage Checkpoint in Mutants Defective in DNA Replication Initiation
In the fission yeast, Schizosaccharomyces pombe, blocks to DNA replication elongation trigger the intra-S phase checkpoint that leads to the activation of the Cds1 kinase. Cds1 is required to both prevent premature entry into mitosis and to stabilize paused replication forks. Interestingly, although...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2555949/ https://ncbi.nlm.nih.gov/pubmed/18667534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-01-0020 |
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