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The Dynamics of Mammalian P Body Transport, Assembly, and Disassembly In Vivo

Exported mRNAs are targeted for translation or can undergo degradation by several decay mechanisms. The 5′→3′ degradation machinery localizes to cytoplasmic P bodies (PBs). We followed the dynamic properties of PBs in vivo and investigated the mechanism by which PBs scan the cytoplasm. Using protein...

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Detalhes bibliográficos
Main Authors: Aizer, Adva, Brody, Yehuda, Ler, Lian Wee, Sonenberg, Nahum, Singer, Robert H., Shav-Tal, Yaron
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2555939/
https://ncbi.nlm.nih.gov/pubmed/18653466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-05-0513
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