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DNA Topoisomerase II Is a Determinant of the Tensile Properties of Yeast Centromeric Chromatin and the Tension Checkpoint

Centromeric (CEN) chromatin is placed under mechanical tension and stretches as kinetochores biorient on the mitotic spindle. This deformation could conceivably provide a readout of biorientation to error correction mechanisms that monitor kinetochore–spindle interactions, but whether CEN chromatin...

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Detalles Bibliográficos
Main Authors: Warsi, Tariq H., Navarro, Michelle S., Bachant, Jeff
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2555933/
https://ncbi.nlm.nih.gov/pubmed/18701701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-05-0547
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