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Different Levels of Bfa1/Bub2 GAP Activity Are Required to Prevent Mitotic Exit of Budding Yeast Depending on the Type of Perturbations

In budding yeast, Tem1 is a key regulator of mitotic exit. Bfa1/Bub2 stimulates Tem1 GTPase activity as a GTPase-activating protein (GAP). Lte1 possesses a guanine-nucleotide exchange factor (GEF) domain likely for Tem1. However, recent observations showed that cells may control mitotic exit without...

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Autors principals: Kim, Junwon, Jang, Selma Sun, Song, Kiwon
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2555922/
https://ncbi.nlm.nih.gov/pubmed/18667533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-02-0149
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