High-frequency deletion in recovered retrovirus vectors containing exogenous DNA with promoters.

We previously described infectious retrovirus vectors constructed from spleen necrosis virus which contain the herpes simplex virus thymidine kinase gene and the mouse alpha-globin gene (K. Shimotohno and H. M. Temin, Nature [London] 299:255-268, 1982). In the present study we report that when TK- c...

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Bibliographic Details
Main Authors: Emerman, M, Temin, H M
Format: Artigo
Language:Inglês
Published: 1984
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC255579/
https://ncbi.nlm.nih.gov/pubmed/6321798
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