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High-frequency deletion in recovered retrovirus vectors containing exogenous DNA with promoters.

We previously described infectious retrovirus vectors constructed from spleen necrosis virus which contain the herpes simplex virus thymidine kinase gene and the mouse alpha-globin gene (K. Shimotohno and H. M. Temin, Nature [London] 299:255-268, 1982). In the present study we report that when TK- c...

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Detalhes bibliográficos
Main Authors: Emerman, M, Temin, H M
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC255579/
https://ncbi.nlm.nih.gov/pubmed/6321798
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