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Characterization of viable mutants of polyomavirus cold sensitive for maintenance of cell transformation.

We mutagenized a cloned fragment of polyoma DNA encoding portions of the middle size (MT) and large T antigens. We regenerated infectious viral genomes containing the mutagenized DNA and tested their transforming ability at 32 and 39 degrees C. We isolated three nontransforming mutants and two mutan...

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Bibliografski detalji
Glavni autori: Templeton, D, Eckhart, W
Format: Artigo
Jezik:Inglês
Izdano: 1984
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC255540/
https://ncbi.nlm.nih.gov/pubmed/6321764
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