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Mutation causing premature termination of the polyoma virus medium T antigen blocks cell transformation.

We used site-specific mutagenesis to introduce a termination codon, TGA, into the reading frame for the polyoma virus medium T antigen. We induced this mutation in a region of the polyoma genome in which the overlapping coding regions for the large and medium TE antigens are translated in different...

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Bibliografiske detaljer
Main Authors: Templeton, D, Eckhart, W
Format: Artigo
Sprog:Inglês
Udgivet: 1982
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC256839/
https://ncbi.nlm.nih.gov/pubmed/6284958
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