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Tumor induction by simian virus 40 in mice is controlled by long-term persistence of the viral genome and the immune response of the host.
Simian virus 40 (SV40), which transforms mouse cells in vitro, has not been previously observed to cause tumors when injected in immunocompetent mice. We have investigated both the fate of the injected virion in mice and several immunological parameters as potential factors controlling tumorigenicit...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
1984
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC255495/ https://ncbi.nlm.nih.gov/pubmed/6319753 |
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