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Influence of the Viral Regulatory Region on Tumor Induction by Simian Virus 40 in Hamsters

Most of the simian virus 40 (SV40) genome is conserved among isolates, but the noncoding regulatory region and the genomic region encoding the large T-antigen C terminus (T-ag-C) may exhibit considerable variation. We demonstrate here that SV40 isolates differ in their oncogenic potentials in Syrian...

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Detalhes bibliográficos
Main Authors: Sroller, Vojtech, Vilchez, Regis A., Stewart, A. Renee, Wong, Connie, Butel, Janet S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224577/
https://ncbi.nlm.nih.gov/pubmed/17977966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01626-07
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