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Glucosamine increases hyaluronic acid production in human osteoarthritic synovium explants

BACKGROUND: Glucosamine (GlcN) used by patients with osteoarthritis was demonstrated to reduce pain, but the working mechanism is still not clear. Viscosupplementation with hyaluronic acid (HA) is also described to reduce pain in osteoarthritis. The synthesis of HA requires GlcN as one of its main b...

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Hlavní autoři: Uitterlinden, EJ, Koevoet, JLM, Verkoelen, CF, Bierma-Zeinstra, SMA, Jahr, H, Weinans, H, Verhaar, JAN, van Osch, GJVM
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553787/
https://ncbi.nlm.nih.gov/pubmed/18786270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-9-120
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