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ShapeFinder: A software system for high-throughput quantitative analysis of nucleic acid reactivity information resolved by capillary electrophoresis

Analysis of the long-range architecture of RNA is a challenging experimental and computational problem. Local nucleotide flexibility, which directly reports underlying base pairing and tertiary interactions in an RNA, can be comprehensively assessed at single nucleotide resolution using high-through...

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Detalhes bibliográficos
Main Authors: Vasa, Suzy M., Guex, Nicolas, Wilkinson, Kevin A., Weeks, Kevin M., Giddings, Morgan C.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553743/
https://ncbi.nlm.nih.gov/pubmed/18772246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1166808
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