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Interactions between Growth Factors and Integrins: Latent Forms of Transforming Growth Factor-β Are Ligands for the Integrin αvβ1

The multipotential cytokine transforming growth factor-β (TGF-β) is secreted in a latent form. Latency results from the noncovalent association of TGF-β with its processed propeptide dimer, called the latency-associated peptide (LAP); the complex of the two proteins is termed the small latent comple...

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Udgivet i:Mol Biol Cell
Principais autores: Munger, John S., Harpel, John G., Giancotti, Filippo G., Rifkin, Daniel B.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Cell Biology 1998
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25536/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9725916/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.9.9.2627
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