Application of a haematopoetic progenitor cell-targeted adeno-associated viral (AAV) vector established by selection of an AAV random peptide library on a leukaemia cell line

BACKGROUND: For many promising target cells (e.g.: haematopoeitic progenitors), the susceptibility to standard adeno-associated viral (AAV) vectors is low. Advancements in vector development now allows the generation of target cell-selected AAV capsid mutants. METHODS: To determine its suitability,...

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Autores principales: Stiefelhagen, Marius, Sellner, Leopold, Kleinschmidt, Jürgen A, Jauch, Anna, Laufs, Stephanie, Wenz, Frederik, Zeller, W Jens, Fruehauf, Stefan, Veldwijk, Marlon R
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553401/
https://ncbi.nlm.nih.gov/pubmed/18789140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-0556-6-12
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