A comprehensive analysis of the naturally occurring polymorphisms in HIV-1 Vpr: Potential impact on CTL epitopes

The enormous genetic variability reported in HIV-1 has posed problems in the treatment of infected individuals. This is evident in the form of HIV-1 resistant to antiviral agents, neutralizing antibodies and cytotoxic T lymphocytes (CTLs) involving multiple viral gene products. Based on this, it has...

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Hauptverfasser: Srinivasan, Alagarsamy, Ayyavoo, Velpandi, Mahalingam, Sundarasamy, Kannan, Aarthi, Boyd, Anne, Datta, Debduti, Kalyanaraman, Vaniambadi S, Cristillo, Anthony, Collman, Ronald G, Morellet, Nelly, Sawaya, Bassel E, Murali, Ramachandran
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2008
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553080/
https://ncbi.nlm.nih.gov/pubmed/18721481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-5-99
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