Neuronal apoptosis by HIV-1 Vpr: contribution of proinflammatory molecular networks from infected target cells

BACKGROUND: Human immunodeficiency virus type 1 (HIV-1) induces neuronal dysfunction through host cellular factors and viral proteins including viral protein R (Vpr) released from infected macrophages/microglia. Vpr is important for infection of terminally differentiated cells such as macrophages. T...

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Autores principales: Guha, Debjani, Nagilla, Pruthvi, Redinger, Carrie, Srinivasan, Alagarsamy, Schatten, Gerald P, Ayyavoo, Velpandi
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3425332/
https://ncbi.nlm.nih.gov/pubmed/22727020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-138
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