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Control of feeding behavior in C. elegans by human G protein-coupled receptors permits screening for agonist-expressing bacteria

G protein-coupled receptors (GPCRs) have a key role in many biological processes and are important drug targets for many human diseases. Therefore, understanding the molecular interactions between GPCRs and their ligands would improve drug design. Here, we describe an approach that allows the rapid...

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Hlavní autoři: Teng, Michelle S., Shadbolt, Paul, Fraser, Andrew G., Jansen, Gert, McCafferty, John
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553035/
https://ncbi.nlm.nih.gov/pubmed/18815363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803290105
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