Human and Yeast Cdk-activating Kinases (CAKs) Display Distinct Substrate Specificities

Cell cycle progression is controlled by the sequential functions of cyclin-dependent kinases (cdks). Cdk activation requires phosphorylation of a key residue (on sites equivalent to Thr-160 in human cdk2) carried out by the cdk-activating kinase (CAK). Human CAK has been identified as a p40(MO15)/cy...

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Detalhes bibliográficos

Publicado no:	Mol Biol Cell
Principais autores:	Kaldis, Philipp, Russo, Alicia A., Chou, Hubert S., Pavletich, Nikola P., Solomon, Mark J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Cell Biology 1998
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25525/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9725911/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.9.9.2545
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