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Human and Yeast Cdk-activating Kinases (CAKs) Display Distinct Substrate Specificities

Cell cycle progression is controlled by the sequential functions of cyclin-dependent kinases (cdks). Cdk activation requires phosphorylation of a key residue (on sites equivalent to Thr-160 in human cdk2) carried out by the cdk-activating kinase (CAK). Human CAK has been identified as a p40(MO15)/cy...

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Hlavní autoři: Kaldis, Philipp, Russo, Alicia A., Chou, Hubert S., Pavletich, Nikola P., Solomon, Mark J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC25525/
https://ncbi.nlm.nih.gov/pubmed/9725911
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