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Substrate specificity of the cdk-activating kinase (CAK) is altered upon association with TFIIH.
The transcription/DNA repair factor TFIIH consists of nine subunits, several exhibiting known functions: helicase/ATPase, kinase activity and DNA binding. Three subunits of TFIIH, cdk7, cyclin H and MAT1, form a ternary complex, cdk-activating kinase (CAK), found either on its own or as part of TFII...
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| Główni autorzy: | , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
1997
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1169767/ https://ncbi.nlm.nih.gov/pubmed/9130708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.7.1628 |
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