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Synthesis and solid-phase application of suitably protected γ-hydroxyvaline building blocks
Recently, an unexpected modified residue, γ-hydroxy-D-valine (D-Hyv), was identified within ribosomally expressed polypeptide chains of four conopeptides from the venoms of Conus gladiator and Conus mus. In order to assemble Hyv-containing peptides, we have explored several routes for the synthesis...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2551766/ https://ncbi.nlm.nih.gov/pubmed/17583956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo070436y |
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