Distal Airways in Mice Exposed to Cigarette Smoke: Nrf2-Regulated Genes Are Increased in Clara Cells

Cigarette smoke (CS) is the main risk factor for chronic obstructive pulmonary disease (COPD). Terminal bronchioles are critical zones in the pathophysiology of COPD, but little is known about the cellular and molecular changes that occur in cells lining terminal bronchioles in response to CS. We su...

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Главные авторы: Adair-Kirk, Tracy L., Atkinson, Jeffrey J., Griffin, Gail L., Watson, Mark A., Kelley, Diane G., DeMello, Daphne, Senior, Robert M., Betsuyaku, Tomoko
Формат: Artigo
Язык:Inglês
Опубликовано: American Thoracic Society 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2551701/
https://ncbi.nlm.nih.gov/pubmed/18441282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2007-0295OC
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