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Downregulation of UT-A1/UT-A3 Is Associated with Urinary Concentrating Defect in Glucocorticoid-Excess State

Excessive glucocorticoid hormone, as occurs with Cushing syndrome, is known to be associated with altered body water homeostasis, but the molecular mechanisms are unknown. In this study, rats treated with daily dexamethasone (Dex) for 14 d provided a model of Cushing syndrome. Compared with control...

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Main Authors: Li, Chunling, Wang, Weidong, Summer, Sandra N., Falk, Sandor, Schrier, Robert W.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Nephrology 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2551574/
https://ncbi.nlm.nih.gov/pubmed/18667732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008010051
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