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ts1, a Paralytogenic mutant of Moloney murine leukemia virus TB, has an enhanced ability to replicate in the central nervous system and primary nerve cell culture.

A temperature-sensitive mutant of Moloney murine leukemia virus TB (MoMuLV-TB), ts1, which is defective in intracellular processing of envelope precursor protein (Pr80env), also possesses the ability to induce hind-limb paralysis in infected mice. To investigate whether ts1 has acquired neurotropism...

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Publicado no:J Virol
Principais autores: Wong, P K, Knupp, C, Yuen, P H, Soong, M M, Zachary, J F, Tompkins, W A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1985
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC255060/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4020966/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.55.3.760-767.1985
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