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Identification of point mutations in the envelope gene of Moloney murine leukemia virus TB temperature-sensitive paralytogenic mutant ts1: molecular determinants for neurovirulence.

ts1, a temperature-sensitive mutant of Moloney murine leukemia virus TB, induces hind-limb paralysis in mice. The DNA of both the ts1 and Moloney murine leukemia virus TB env genes has been sequenced, and the encoded amino acid sequences have been deduced from the DNA sequences. Four amino acids in...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Szurek, P F, Yuen, P H, Jerzy, R, Wong, P K
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC250539/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3334748/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.62.1.357-360.1988
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