Alteration from T- to B-cell tropism reduces thymic atrophy and cytocidal effects in thymocytes but not neurovirulence induced by ts1, a mutant of Moloney murine leukemia virus TB.

The ts1 mutant of Moloney murine leukemia virus TB causes degenerative neurologic and immunologic disease in mice, characterized by development of spongiform encephalomyelopathy resulting in hindlimb paralysis, marked thymic atrophy associated with immunodeficiency, and generalized body wasting. To...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Wong, P K, Szurek, P F, Floyd, E, Saha, K, Brooks, B R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52637/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1924361/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.20.8991
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!