Herpes simplex virus 1 mutant deleted in the alpha 22 gene: growth and gene expression in permissive and restrictive cells and establishment of latency in mice.

R325-beta TK+, a herpes simplex virus 1 mutant carrying a 500-base-pair deletion in the alpha 22 gene and the wild-type (beta) thymidine kinase (TK) gene, was previously shown to grow efficiently in HEp-2 and Vero cell lines. We report that in rodent cell lines exemplified by the Rat-1 line, plating...

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Detalles Bibliográficos
Main Authors: Sears, A E, Halliburton, I W, Meignier, B, Silver, S, Roizman, B
Formato: Artigo
Idioma:Inglês
Publicado: 1985
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC254938/
https://ncbi.nlm.nih.gov/pubmed/2991560
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