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The Spindle Checkpoint of Budding Yeast Depends on a Tight Complex between the Mad1 and Mad2 Proteins

The spindle checkpoint arrests the cell cycle at metaphase in the presence of defects in the mitotic spindle or in the attachment of chromosomes to the spindle. When spindle assembly is disrupted, the budding yeast mad and bub mutants fail to arrest and rapidly lose viability. We have cloned the MAD...

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Hlavní autoři: Chen, Rey-Huei, Brady, D. Michelle, Smith, Dana, Murray, Andrew W., Hardwick, Kevin G.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 1999
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC25492/
https://ncbi.nlm.nih.gov/pubmed/10436016
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