Restricted changes in the adenovirus DNA-binding protein that lead to extended host range or temperature-sensitive phenotypes.
Human adenovirus fails to multiply efficiently in monkey cells owing to a block to late viral gene expression. Ad2hr400 through Ad2hr403 are a set of host range (hr) mutants which were selected for their ability to readily grow in these cells at 37 degrees C. The mutations responsible for this exten...
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| Publicado en: | J Virol |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
1985
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC254916/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3925161/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.55.1.206-212.1985 |
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