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Isolation and characterization of a viable adenovirus mutant defective in nuclear transport of the DNA-binding protein.

The isolation and characterization of an adenovirus mutant, Ad5dl802r1, containing two independent deletions in the 72-kilodalton (kDa) DNA-binding protein (DBP) gene is described. The two deletions remove amino acids 23 through 105 of DBP, resulting in the production of a 50-kDa product. Expression...

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Udgivet i:J Virol
Principais autores: Cleghon, V, Voelkerding, K, Morin, N, Delsert, C, Klessig, D F
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC250647/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2523000/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.5.2289-2299.1989
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