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The Doa4 Deubiquitinating Enzyme Is Required for Ubiquitin Homeostasis in Yeast

Attachment of ubiquitin to cellular proteins frequently targets them to the 26S proteasome for degradation. In addition, ubiquitination of cell surface proteins stimulates their endocytosis and eventual degradation in the vacuole or lysosome. In the yeast Saccharomyces cerevisiae, ubiquitin is a lon...

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Auteurs principaux: Swaminathan, Sowmya, Amerik, Alexander Y., Hochstrasser, Mark
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 1999
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC25490/
https://ncbi.nlm.nih.gov/pubmed/10436014
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