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The Doa4 Deubiquitinating Enzyme Is Functionally Linked to the Vacuolar Protein-sorting and Endocytic Pathways

The Saccharomyces cerevisiae DOA4 gene encodes a deubiquitinating enzyme that is required for rapid degradation of ubiquitin–proteasome pathway substrates. Both genetic and biochemical data suggest that Doa4 acts in this pathway by facilitating ubiquitin recycling from ubiquitinated intermediates ta...

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Detalhes bibliográficos
Main Authors: Amerik, Alexander Y., Nowak, Jonathan, Swaminathan, Sowmya, Hochstrasser, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC14998/
https://ncbi.nlm.nih.gov/pubmed/11029042
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