Loading...
Site-specific incorporation of unnatural amino acids into urate oxidase in Escherichia coli
Urate oxidase catalyzes the oxidation of uric acid with poor solubility to produce 5-hydroxyisourate and allantoin. Since allantoin is excreted in vivo, urate oxidase has the potential to be a therapeutic target for the treatment of gout. However, its severe immunogenicity limits its clinical applic...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Cold Spring Harbor Laboratory Press
2008
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2548377/ https://ncbi.nlm.nih.gov/pubmed/18596202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.034587.108 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|