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Toward the semisynthesis of multidomain transmembrane receptors: Modification of Eph tyrosine kinases

Expressed protein ligation (EPL) is a protein engineering approach that allows the modification or assembly of a target protein from multiple recombinant and synthetic polypeptides. EPL has been previously used to modify intracellular proteins and small integral membrane proteins for structural and...

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Autors principals: Singla, Nikhil, Himanen, Juha Pekka, Muir, Tom W., Nikolov, Dimitar B.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2548361/
https://ncbi.nlm.nih.gov/pubmed/18628240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.035659.108
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