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Probing the reaction mechanism of the D-ala-D-ala dipeptidase, VanX, by using stopped-flow kinetic and rapid-freeze quench EPR studies on the Co(II)-substituted enzyme

In an effort to probe the reaction mechanism of VanX, the D-ala-D-ala dipeptidase required for high-level vancomycin resistance in bacteria, stopped-flow kinetic and rapid-freeze quench EPR studies were conducted on the Co(II)-substituted enzyme when reacted with D-ala-D-ala. The intensity of the Co...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Matthews, Megan L., Periyannan, Gopalraj, Hajdin, Christine, Sidgel, Tara K., Bennett, Brian, Crowder, Michael W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2547881/
https://ncbi.nlm.nih.gov/pubmed/17017774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja0627343
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