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Selectivity for d-Lactate Incorporation into the Peptidoglycan Precursors of Lactobacillus plantarum: Role of Aad, a VanX-Like d-Alanyl-d-Alanine Dipeptidase
Lactobacillus plantarum produces peptidoglycan precursors ending in d-lactate instead of d-alanine, making the bacterium intrinsically resistant to vancomycin. The ligase Ddl of L. plantarum plays a central role in this specificity by synthesizing d-alanyl-d-lactate depsipeptides that are added to t...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1913409/ https://ncbi.nlm.nih.gov/pubmed/17400741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01829-06 |
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