Selectivity for d-Lactate Incorporation into the Peptidoglycan Precursors of Lactobacillus plantarum: Role of Aad, a VanX-Like d-Alanyl-d-Alanine Dipeptidase

Lactobacillus plantarum produces peptidoglycan precursors ending in d-lactate instead of d-alanine, making the bacterium intrinsically resistant to vancomycin. The ligase Ddl of L. plantarum plays a central role in this specificity by synthesizing d-alanyl-d-lactate depsipeptides that are added to t...

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Hlavní autoři: Deghorain, Marie, Goffin, Philippe, Fontaine, Laetitia, Mainardi, Jean-Luc, Daniel, Richard, Errington, Jeff, Hallet, Bernard, Hols, Pascal
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2007
Témata:
Enzymes and Proteins
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913409/
https://ncbi.nlm.nih.gov/pubmed/17400741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01829-06
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