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Substrate Stiffness Affects the Functional Maturation of Neonatal Rat Ventricular Myocytes

Cardiac cells mature in the first postnatal week, concurrent with altered extracellular mechanical properties. To investigate the effects of extracellular stiffness on cardiomyocyte maturation, we plated neonatal rat ventricular myocytes for 7 days on collagen-coated polyacrylamide gels with varying...

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Detalhes bibliográficos
Main Authors: Jacot, Jeffrey G., McCulloch, Andrew D., Omens, Jeffrey H.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2547444/
https://ncbi.nlm.nih.gov/pubmed/18586852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.124545
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